Thrills and twists marked the opening round of the Italian F.4 Championship at the Misano World Circuit, as part of the season-launching ACI Racing Weekend. At the start, confusion caused by several jump starts, including one by Germany’s Maxim Rehm (US Racing), reshuffled the race's early stages. Rehm made a quick getaway and led the opening laps but was later overtaken by Prema Racing drivers Sebastian Wheldon and Salim Hanna before receiving a 10-second penalty for the irregular start.

At the conclusion of the opening day of the ACI Racing Weekend in Misano, host of the inaugural round of the 2025 Italian F.4 Championship, the 41 drivers entered in the series faced off in the qualifying challenge, taking to the track in two groups. The results from both sessions will set the grid for three of the four races scheduled over the weekend. The final race, set for Sunday evening, will feature only the top 36 drivers, selected based on points and placements earned in the first three races.